Kuo’s art practice includes a diverse range of genres, including painting, video, installation, and performance. She uses art to express the missing elements or insufficiencies between her own experiences in life and what is considered Big History, including issues involving her personal memories, the Cold War, and the circumstances she encounters. Using the notion of “missing or lacking” to bring forth already determined historical predicaments, Kuo uses trauma and disappointments to support a medley of metaphors, which has become a notable feature in her artworks. She seeks to push or correct “existing” concepts, in order for them to be more aligned with reality and the local mentality.